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胡椒堿
分析標(biāo)準(zhǔn)品,HPLC≥98%
Piperine
CAS號(hào)：94-62-2
分子式：C17H19NO3
分子量：285.34
MDL：MFCD00005839
貨號(hào) | 規(guī)格/參數(shù)/品牌 | 價(jià)格 | 貨期 |
YJ-B20516-20mg | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥180.00 | 現(xiàn)貨 |
YJ-B20516-1g | 分析標(biāo)準(zhǔn)品,HPLC≥98% | ￥1300.00 | 現(xiàn)貨 |
JS30603-1g | BR，98% | ￥160.00 | 現(xiàn)貨 |
JS30603-5g | BR，98% | ￥270.00 | 現(xiàn)貨 |
JS30603-25g | BR，98% | ￥700.00 | 現(xiàn)貨 |
JS30603-100g | BR，98% | ￥1800.00 | 現(xiàn)貨 |
A10337-20mg | 分析標(biāo)準(zhǔn)品,含量98.5%，可溯源 | ￥310.00 | 現(xiàn)貨 |
JT25317-1g | ≥98%(HPLC) | ￥168.00 | 2-3天 |
JT25317-5g | ≥98%(HPLC) | ￥309.00 | 現(xiàn)貨 |
JT25317-25g | ≥98%(HPLC) | ￥665.00 | 2-3天 |
產(chǎn)品介紹
Piperine是從胡椒中分離的天然生物堿，可以抑制P-glycoprotein and CYP3A4的活性，在HeLa細(xì)胞中的IC50值為61.94±0.054 μg/mL。
熔點(diǎn)：131-135℃(lit.)
沸點(diǎn)：498.524℃ at 760 mmHg
外觀：白色晶體粉末
溶解性：DMSO:50mg/mL(175.23mM;Needultrasonic)
敏感性：對(duì)光,濕度,空氣敏感
儲(chǔ)存條件：2-8℃
注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。
參考文獻(xiàn)(19篇)
19. [IF=6.3] Yeye Hu et al."Piperine Improves DSS-Induced Colitis in Mice via Inhibition of Inflammation and Modulation of Gut Microbiota."PHYTOTHERAPY RESEARCH.2025 Jun;:
18. [IF=4.9] Dongyan Guan et al."The Extract of Piper nigrum Improves the Cognitive Impairment and Mood in Sleep-Deprived Mice Through the JAK1/STAT3 Signalling Pathway."INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES.2025 Jan;26(5):1842
17. [IF=8.2] Kangyun Zhao et al."Investigation of the formation mechanism of the pepper starch-piperine complex."INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES".2024 May;268:131777
16. [IF=5.8] Chang Yang et al."Umbilical therapy for promoting transdermal delivery of topical formulations: Enhanced effect and underlying mechanism."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2024 Mar;652:123834
15. [IF=6.51] Jiawei Han et al."Mechanistic insight into gel formation of co-amorphous resveratrol and piperine during dissolution process."INTERNATIONAL JOURNAL OF PHARMACEUTICS.2023 Mar;634:122644
14. [IF=3.756] Jiawei Han et al."Self-gelation involved in the transformation of resveratrol and piperine from a co-amorphous system into a co-crystal system."CRYSTENGCOMM.2022 Jul;:
13. [IF=7.419] Baoyi Chen et al."Protective effect of oxyberberine against acute lung injury in mice via inhibiting RhoA/ROCK signaling pathway."BIOMEDICINE & PHARMACOTHERAPY.2022 Sep;153:113307
12. [IF=6.321] Yanjie Liu et al."Crystal Structure, Solubility, and Pharmacokinetic Study on a Hesperetin Cocrystal with Piperine as Coformer."Pharmaceutics. 2022 Jan;14(1):94
11. [IF=3.779] Xingming Hou et al."Natural Piperine Improves Lipid Metabolic Profile of High-Fat Diet-Fed Mice by Upregulating SR-B1 and ABCG8 Transporters."J Nat Prod. 2021;84(2):373–381
10. [IF=6.023] Maiquan Li et al."Discovery of Keap1?Nrf2 small?molecule inhibitors from phytochemicals based on molecular docking."Food Chem Toxicol. 2019 Nov;133:110758
9. [IF=2.419] Tingting Gao et al."Characterization of piperine metabolites in rats by ultra-high-performance liquid chromatography with electrospray ionization quadruple time-of-flight tandem mass spectrometry."Rapid Commun Mass Sp. 2017 Jun;31(11):901-910
8. [IF=3.046] Liwei Dong et al."Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1."Oncotargets Ther. 2015; 8: 3649–3664
7. [IF=5.875] Ruoning Wang et al."Involvement of metabolism-permeability in enhancing the oral bioavailability of curcumin in excipient-free solid dispersions co-formed with piperine."Int J Pharmaceut. 2019 Apr;561:9
6. Gao, Tingting, et al. "Characterization of piperine metabolites in rats by ultra‐high‐performance liquid chromatography with electrospray ionization quadruple time‐of‐flight tandem mass spectrometry." Rapid Communications in Mass Spectrometry 31.11 (2017):
5. 陸昕怡, 韓加偉, 李文,等. 姜黃素/胡椒堿固體分散體的制備及體外評(píng)價(jià)[J]. 現(xiàn)代中藥研究與實(shí)踐, 2018, 032(003):49-53.
4. 黃容, 陸昕怡, 韓加偉,等. 姜黃素-胡椒堿固體分散體的制備與生物利用度研究. 中草藥.
3. 陳永昆, 姜亭亭, 吉世松,等. 胡椒堿聯(lián)合硝苯地平對(duì)家兔血壓的影響[J]. 臨床醫(yī)學(xué)研究與實(shí)踐, 2017, 2(033):10-11.
2. 宋思維, 唐艷紅. 胡椒堿對(duì)缺氧復(fù)氧心肌細(xì)胞的保護(hù)作用及機(jī)制研究[J]. 嶺南心血管病雜志, 2019, 25(01):113-118.
1. 嚴(yán)玉玲, 郭焰, 豆一玲. 胡椒堿分離純化工藝的研究[J]. 中國農(nóng)業(yè)信息, 2015(17):165.
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